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A nearly100 times higher dose (250–1000 mg/m2 BSA)of Mtx is infused i.v. Additional high-quality trials are required to establish the optimal dilution ofeach of the serotype A BoNT products. (2006) studied the cumulative incidenceand predictors of new-onset seizures in mild Alzheimer’sdisease (AD), with a cohort followed prospectively.
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